Description

This circuit is an electronic realization of the original -cell model equations which is achieved with the use of several blocks. That blocks are LPF, multiplier, Tran’s conduction, thermo-coder and comparator. Each block consists of the different current value which will give the different power value of the each block. Based on that the total B cell power consumption can be reducing for the implementation of Bio-Inspired Glucose Control in Diabetes. An evaluation of a simple model including external perturbations was evaluated for its usefulness in predicting patient behavior. The model proposed is derived from Bergman’s minimal model and is structurally identifiable. The optimization was carried out on data gathered using CGMS (Medtronic Minimed) on 7 subjects. The model was also identified after performing a model based signal enhancement. The results obtained identifying before and after signal enhancement show a promising reduction in the variation coefficient of the estimated parameters. This reduction is expected to be useful in the design of a closed loop controller for subcutaneous insulin delivery. It can also be concluded from the precision of these parameters that even though the data collected correspond to oral glucose challenges, the model is able to follow these dynamics although initial values were obtained after an IVGTT. Nevertheless, it looks reasonable to estimate initial values for the real tests being modelled. Future directions of this study will include this improvement. The aim is therefore to recover the signal from a set of noise contaminated measurements by imposing a set of properties that the signal is hypothesized to possess.